Anemias

Question 1

macrocytic megaloblastic anemias

Answer 1

vit b12
folate
orotic aciduria

Question 2

non-megaloblastic macrocytic anemias

Answer 2

aplastic anemia
diamond-blackfan anemia
bone marrow infiltration
hypothyroidism
fanconi anemia
liver disease

Question 3

normocytic anemias

Answer 3

blood loss
dec. RBC production
incr. RBC destruction
inherited hemolytic anemias
acquired hemolytic anemias

Question 4

blood loss as cause of normocytic anemis

Answer 4

removal from the blood
acute blood loss
splenic sequestration

Question 5

dec. RBC prod. as cause of normocytic anemia

Answer 5

anemia of chronic disease
transient erythroblastopenia of childhood
chronic renal failure
malignant infiltration of the bone marrow
parvo b19 aplastic crisis
myelosuppressive agent drug toxicity

Question 6

inherited hemolytic anemias

Answer 6

abnl hemoglobin
sickle cell 
thalessema
RBC enzyme disorders
G6PD def.
pyruvate kinase deficiency
RBC membrane disorders
hereditary spherocytosis
hereditary elliptocytosis

Question 7

acquired hemolytic anemias

Answer 7

antibody mediated anemias
autoimmune hemolytic anemias
isoimmune hemolytic anemias
microangiopathic hemolytic anemias
HUS 
DIC
paroxysmal nocturnal hemoglobuinuria

Question 8

microcytic anemias

Answer 8

Fe deficiency
severe lead poisoning
thalessemia syndromes
sideroblastic anemia
ACD

Question 9

transient erythroblastopenia of childhood

Answer 9

normocytic anemia
bone marrow suppression
peak incidence 2 yo
nL peripheral smear
reticulocytopenia
few erythroid precursors, normal myeloid/plt precursors