anesthesia

Question 1

Oliver Wendell Holmes

Answer 1

coined “anesthesia” when ether was discovered

Question 2

reversal agents for muscle relaxants

Answer 2

edrophonium, neostigmine, pyridostigmine

Question 3

antidotes for benzodiazepines (valium, versad, midazolam)

Answer 3

flumazenil (still retain intraop amnesia)

Question 4

protein receptor theory

Answer 4

-certain # of receptor sites in CNS need to be filled before movement to noxious stimuli is stopped

Question 5

Meyer-Overton Theory

Answer 5

• aka critical volume hypothesis

- relationship bt lipid solubility and anesthetic potentcy

Question 6

endogenous endorphin theory

Answer 6

anesthesia=opiate like substance

Question 7

4 stages of anesthesia progression

Answer 7

• initial administration
• excitement
• intrasx
• failure/death

Question 8

cricoid pressure

Answer 8

• occlude esophagus to prevent aspiration during ET placement (esp in emergency cases/crash induction)
• downward pressure w/ thumb and index on cricoid cartilage

Question 9

MH s/s

Answer 9

• ****inc. end tidal CO2
• tachycardia
• jaw muscle rigid
• inc. K, lactic acidosis, O2 demand, temp (late), intracellular calcium

Question 10

common MH trigger

Answer 10

succinylcholine