ANGINA PECTORIS Flashcards

(42 cards)

1
Q

Angina pectoris

A

Chest pain / discomfort caused by myocardial ischemia

Mismatch O2 supply and Demand

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2
Q

Infaction

A

NO O2

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3
Q

Ischemia

A

πŸ‘‡πŸ»O2

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4
Q

Disease

A

Coronary artery disease

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5
Q

Pathophysiology

A

Atherosclerosis

Build up clot

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6
Q

Manifestation of Coronary Artery disease

A
  • Acute coronary syndrome
  • Chronic stable angina pectoris
  • Prinzmetal angina
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7
Q

Acute manifestation CAD

A

-Acute coronary syndrome

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8
Q

Types of acute coronary syndrome

A
Acute MI
  -STEMI =occlusive
  -NSTEMI=non occlusive
Unstable Angina Pectoris
  -Rest Angina
  -crescendo
  -new onset
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9
Q

Acute MI

A

☝🏻️cardiac biomarkers
Troponin
CK

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10
Q

Unstable Angina Pectoris

A

(-)Cardiac Biomarkers

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11
Q

STEMI? And indicate the drugs

A

Completely block

  • Fibrinolytics
  • anticoagulant
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12
Q

NSTEMI? And what drugs

A

Partially block

Anticoagulants

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13
Q

Chronic stable angina pectoris

☝🏻️ O2 _____?

A

☝🏻️O2 demand

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14
Q

Vasopasm

A

Prinzmetal angina

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15
Q

Aprroach to managemt

A

☝🏻️O2 supply

πŸ‘‡πŸ»O2 demand

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16
Q

Give mngt in ☝🏻️O2 supply

A
  • percutaneous transluminal coronary angioplasty
  • coronary artery bypass grafting
  • coronary vasodilators
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17
Q

Give the mngt in πŸ‘‡πŸ»O2 demand

A
  • nitovasodilators
  • beta blockers
  • CCB’s
18
Q

What happen if the O2 demand πŸ‘‡πŸ»

A

πŸ‘‡πŸ»HR
πŸ‘‡πŸ»SV
πŸ‘‡πŸ»SVR

19
Q

What is the MOA of nitrovasodilators

A

☝🏻️NO but requires SH group

20
Q

What are the effects that may occur in nitrovasodilators having a Low dose

A

Peripheral venodilation

πŸ‘‡πŸ»preload
πŸ‘‡πŸ»O2 demand

21
Q

What are the effects that may occur in nitrovasodilators having a High dose

A

Arteriolar vasodilation

☝🏻️O2 supply

22
Q

What is the SE in high dose nitrovasodilators

A

Reflex tachycardia

☝🏻️O2 demand

23
Q

What is the remedy in high dose in nitrovasodilators

A

Beta blockers

24
Q

Drugs in nitrovasodilators

A

Very short acting
Short acting
Intermediate acting
Long acting agents

25
Very short acting Duration
Amyl nitrite <5-10mins
26
Short acting agents Duration
NTG ISDN 10-30mins
27
Intermediate acting Duration
NTG SR tab ISDN po tab 5-8hrs
28
Long acting agents Duration
NTG transdermal patch ISDN SR tab ISMD po tab 10-24hrs
29
SE of nitrovasodilators
Hypotension Migraine like HA Tolerance Methemoglobinemia
30
Beta blockers
DOC OF CSAP
31
Calcium channel blocker
(Non DHP) DOC FOR PRINZMETAL ALT. CSAP
32
How many minutes of acute coronary syndrome occur in chest pain
20 mins
33
Chronic stable angina pectoris how many minutes chestpain
Chest pain 2-5 mins during or after physical exertion and emotional stress
34
Chronic manifestation of CAD
CSAP
35
Prinzmetal angina πŸ‘‡πŸ» what?
πŸ‘‡πŸ»O2 supply
36
Mngt of acute coronarysyndrome
IV infusion
37
Mngt of CSAP
PO or Trandermal
38
Mngt of prinzmetal
IV infusion + beta blockers
39
Mngt of HF
Hydralazine + ISDN
40
Alternative in mngt of HTN emergencry crisis
IV infusion
41
What MOA is sildenafil
(-) phosphodiesterase
42
SE of sildenafil
Hypotension Migraine like HA Tolerance