Lidocaine
Class 1B
little effect on normal myocardium
fast
Phenytoin
class 1B
Mexiletine
Class 1B
Flecainide
Class 1C
effects normal+damaged myocardium
non-selective
Propafenone
Class 1C
Quinidine
Class 1A
moderate blocker
blocks K efflux
Procainamide
Class 1A
Disopyramide
Class 1A
Atenolol
Class II
selective
Metaprolol
Class II
selective
Bisoprolol
Class II
selective
Propranolol
Class II
non-selective
Amiodarone
Class III
Dronedarone
Class III
Vernakalant
Class III
Verapamil
Class IV
Diltiazem
Class IV
Class system name
Vaughan Williams Classification
what do antiarrhythmic agents do?
supress abnormal cardiac electrical activity
Class I
Na channel blockers
Are class I fast or slow response?
fast
Class I: non-nodal or nodal?
Non-nodal
how do Class I work?
depress phase 0, extend A.P duration and refractory period, supress excitability, decrease abnormal and triggered
What does Class IA additionally block
K channels (extends A.P, delays phase 3)
