Anticancer - Toxicities Flashcards by Anar Itrabarkahc

Q

What causes Hemorrhagic cystitis

A

Cyclophosphamide

Ifosfamide

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Q

Bleomycin

A

Pulm fibrosis

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Q

Cisplatin

A

Nephrotoxicity

Deafness

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Q

L-asparaginase

A

Pancreatitis

Bleeding

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Q

Prevent Hemorrhagic cystitis

A

Mesna

Maintain high urine output

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Q

Prevent cisplatin toxicity

A

Hydration

Amifostine

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Q

What causes Dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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Q

Vincristine

A

Peripheral Neuropathy

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Q

What causes BM supression

A

Etoposide
Vinblastine
MTX

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Q

Prevent Dilated cardiomyopathy

A

Dexrazoxane

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Q

Prevent MTX BM supression

A

Leucovorin (THF rescue)

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Q

Prevent BM supression by Etoposide or Vinblastine

A

Filgrastim (GM-CSF)

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