Anticoagulants MOA

Question 1

Aspirin

Answer 1

Non reversible COX1 and COX 2 inhibitor

Question 2

Warfarin

Answer 2

Vitamin K antagonist

Question 3

Clopidogrel

Answer 3

ADP receptor antagonist

Question 4

Rivaroxaban

Answer 4

Direct Xa

Question 5

Fondaparinoux

Answer 5

Activates antithrombin III, which in turn potentiates the inhibition of coagulation factors Xa. It is given subcutaneously.

Question 6

Dabigatran

Answer 6

Dabigatran: direct thrombin inhibitor

Question 7

Bivalirudin

Answer 7

direct thromin IN IN

Question 8

Rixaroxaban

Answer 8

Binds directly to factor Xa

Question 9

Heparin

Answer 9

Inhibit antithrombin III
action Activates antithrombin III. Forms a complex that inhibits thrombin, factors Xa, IXa, Xia and XIIa

Question 10

LMWH

Answer 10

Activates antithrombin III. Forms a complex that inhibits factor Xa

Question 11

Abciximab

Answer 11

Glycoprotein IIb/IIIa receptor antagonist