Antimanic medications
Lithium
Antipsychotics
antiepileptics
Drug of choice for 1st time mania?
Lithium
Therapeutic range of Lithium
0.6-1.2meq/L
Antimanics…
action-salt that alters sodium transports Orally absorbed well in GI peak 30min-3 hours excreted from kidneys
Contraindications for antimanics
renal or cardiac disease, leukemia, diuretics, metabolic disorders
not w pregnancy
not w breast feeding
AE of antimanics
related to serum levels
toxic above 1.5
Ekg changes
DD antimanics
halopridol
caramazapine
NSsaid-increase lithium
antacid decrease litium effectiveness
Ni for antimanics
monitor serum, give food to decrease GI irritation
maintain normal salt and fluid
teach
safety