Therapeutic class
mood stabilizer
Example
lithium (Eskalith)
Mechanism of Action
affects sodium transport across cell membranes
Actions and Uses
primary use: acute treatment of manic or mixed bipolar disorder
effective for purely manic or purely depressive episodes
acts like sodium in body (excessive sweating or dehydration can cause toxicity)
Adverse Effects
Headache lethargy fatigue recent memory loss nausea and vomiting anorexia abdominal pain diarrhea dry mouth muscle weakness hand tremors reversible leukocytosis nephrogenic diabetes insipidus
Interactions
Diuretics,NSAIDS,COX-2 inhibitors,methyldopa, phenytoin
SSRIs, SNRIs and MAOIs ( serotonin syndrome)
Black Box Warning
Requires close monitoring to prevent toxicity
Pregnancy Category
D
if pregnant can use lamotrigine (Lamictal)