Appendix

Question 1

Ackerman’s 9 basic patterns of inflammatory skin disease

Answer 1

1. Superifical perivascular dermatitis
2. Superficial and deep perivascular dermatitis (includes spong derm, psoriasiform derm, and interface derm)
3. Vasculitis
4. Nodular and diffuse dermatitis
5. Intraepidermal vesicular and pustular dermatitis
6. Subepidermal vesicular dermatitis
7. Folliculitis and perifolliculitis
8. Fibrosing dermatitis
9. Panniculitis

Question 2

Leboit’s 5 patterns of interface dermatitis base on epidermal changes

Answer 2

1. Acute cytotoxic
   
   • EM, TEN, connective tissue disease, fixed drug, morbilliform drug, pityriasis lichenoides. early GVHD, subacute radiation dermatitis, eruption of lymphocyte recovery
   • basketweave orthokeratosis
2. Premature terminal differentiation
   
   • LP, wound healing, lichenoid GVHD, lichenoid drug, lichenoid keratosis, DLE
   • basilar squamatization, jagged rete ridges
3. Irregular epidermal hyperplasia
   
   • hypertrophic LP, verrucous LE
4. Psoriasiform +/- spongiosis
   
   • MF, syphilis, lichen aureus, lichen striatus, urticarial pemphigoid, porokeratosis, eraly lichen sclerosus
5. Atrophic

• LP, poikilodermatous MF, regression of melanoma or superficial BCC

Question 3

Papillomatosis

Answer 3

Epidermal hyperplasia in which there are also projections of the dermal papillae above the skin surface (e.g., warts)

Question 4

Vacuolar alteration

Answer 4

Minute spaces immediately above or below the basement membrane

Question 5

spongiform pustule

Answer 5

accumulation of neutrophils within and between keratinocytes or stratum corneum (e.g., Munro’s microabscesses)