What is satiation?
The process which develops during eating and brings an episode of eating to a close (during meals)
What is satiety?
The state of inhibition over further eating (between meals)
What things regulate appetite?
- neurochemicals
- GIT: nutrients, hormones, stomach (stretch receptors)
- reward system
- sensory factors
- fat stores (hormones)
What is the main regulator of appetite control?
The hypothalamus
What leads to passive overconsumption?
The brain overriding ‘full signals’ (gastric distension is a weak signal)
Desire to eat, rather than hunger, can override this full signal
What are the 2 systems for appetite?
- Feeding system - initiates feeding from lateral hypothalamus
- Satiety system - stops feeding from ventromedial hypothalamus
Serotonin, leptin, insulin, CCK, PYY-1, GLP, AA, glucose - promote or reduce eating?
Reduce eating
Galanin, neuropeptide Y, B-endorphin, dynorphin, dopamine, norepinephrine, gherkin - promote or decrease eating?
Promote eating
What does neuropeptide Y stimulate?
Stimulates food intake
