Approximate pKa values for functional groups Flashcards by Sarah Preston

Q

carboxylic acid (R-COOH)

A

pKa ~5

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Q

phenol (Ar-OH)

A

pKa ~10

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Q

alcohol and water (R-OH)

A

pKa ~15

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Q

ketone (alpha hydrogen)

A

pKa ~20

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Q

ester (alpha hydrogen)

A

pKa ~25

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Q

terminal alkyne

A

pKa ~25

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Q

amine (R2N-H)

A

pKa ~35

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Q

alkene (vinylic hydrogen)

A

pKa ~45

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Q

alkane

A

pKa ~60

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Q

beta-diketone (alpha H between carbonyls)

A

pKa ~10

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Q

beta-diester (alpha H between carbonyls)

A

pKa ~15

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Q

ammonium ion (R3-N+-H)

A

pKa ~10

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