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argf Flashcards

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1
Q
  1. Which one of the following antiepileptic medications is considered a controlled
    substance?
A

Phenobarbital (Luminal)

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2
Q

Which antidepressant is contraindicated in patients with a seizure disorder?

A

Bupropion (Wellbutrin)

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3
Q

Which of the following medications is NOT recommended for children under 12 years of
age?

A

Tramadol (ultram)

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4
Q
  1. Which of the following antidepressants is associated with the most weight gain?
A

Mirtazapine (Remeron)

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5
Q
  1. Acetaminophen is contraindicated in which of the following conditions?
A

Active hepatitis

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6
Q

Which of the following antiepileptic medications is known to cause a significant amount
of cognitive impairment and is associated with an increased risk of nephrolithiasis if th
patient is not adequately hydrated?

A

Topiramate (Topamax)

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7
Q

You give a patient hydrocodone/acetaminophen after care, what common side effect
should we warn zer about?

A

Constipation

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8
Q
  1. Endo patient who has history of NSAID induced GI bleeds, kidney disease and active
    hepatitis, what is the best pain management regimen?
A

Oxycodone 5mg q6 hrs PRN x 3 days supply.

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9
Q

Which of the following medications is used for management of chronic neuropathic pain
and has been used for pre-operative and peri-operative analgesia in dental school and
other surgical procedures?

A

Pregabalin (Lyrica)

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10
Q
  1. Carbamazepine (Tegretol) and oxcarbazepine (Trileptal) are both antiepileptic
    medications that can contribute to a condition known as syndrome of inappropriate
    antidiuretic hormone (SIADH). One result from this condition is to develop a
    hypervolemic _________
A

Hyponatremia

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11
Q

Which antidepressant is recommended as first line therapy in treatment guidelines for
depression?

A

Venlafaxine (Effexor)
- Mirtazapine (Remeron)
- Escitalopram (Lexapro)

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12
Q
  1. Which of the following antidepressants is associated with the most weight gain?
A

Zoloft

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13
Q
  1. Which of the following Rx is not recommended for kids less than 12 y.o.?
A

Tramadol- w/ acetaminophen is contraindicated for children younger than 12 due to
variability in metabolism.

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14
Q
  1. Requi9red on written prescription for oxycodone?
A

Dentist full name, address, signature, and patient full name and address ( A and C)

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15
Q

Seizure disorder type referred as “drop attack”, pt. wear helmet to protect their head?

A

Atonic

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16
Q
  1. Which antidepressant has been associated with bruxism?
A

Fluoxetine (Prozac)

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17
Q

Boi is treated for focal seizures with dysconitive features and 2 nd generalization with
carbamazepine. Boi is stabilized, no seizure after 2 weeks on carbamazepine, after 4
weeks, seizure frequency increases, durg level 5.6 mg/L. Wut the fak happened?

A

Metabolism autoinduction by carbamazepine.

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18
Q

Which of the following antiepileptic meds is known to cause sig. amounts of cognitive
impairment and associated with nephrolithiasis?

A

Topiramate (Topamax)

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19
Q
  1. Antidepressant’s MOA includes both serotonin and norepinephrine reuptake inhibitor?
A

Venlafaxine (efflexor)

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20
Q
  1. Recommended dose of acetaminophen by healthcare provider?
A

3mg, Elderly 2-3mg

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21
Q
  1. What type of a seizure is characterized by randomly falling and needing a helmet?
A

Atonic

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22
Q
  1. AD with most weight gain?
A

TCA- amitriptyline

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23
Q

Chronic and neuropathic pain?

A

TCA- amtryptiline

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24
Q

Venlafaxine (Effexor)?

A

Blocks the ne/5ht pump because it is an SNRI

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25
Benzos can cause _______ with overdose?
CNS and respiratory depression
26
Akathisia is more common than other EPS
62. Ariprazole-
27
increased prolactin (galactorrhea, gynecomastia etc)
Rispiridone:
28
Haloperidol:
highest risk for EPS
29
Sialorrhea
Clozapine:
30
Antidepressant with the least weight gain?
Bupropion
31
Drowsy, sedation, psychomotor impairment, blurred vision, ataxia, impaired memory, risk for drug-to-drug interaction. No oral effects.
Question about main side effects of Benzos:
32
Which of the following adverse effects is specifically associated with the use of inhaled corticosteroids.
Oral candidiasis
33
GABA-A is coupled to what channels and is the mechanistic target for the therapeutic benefits of benzodiazepines?
CHLORIDE
34
When prescribing an oral corticosteroid for its anti-inflammatory effects and pain management to treat an inflammatory dental condition, what instructions should be provided for administration?
Take in the morning with food.
35
The seizure medication that is most associated with a rash and requires a conservative gradual dose titration when used with enzyme inhibitors or valproic acid?
Lamotrigine (Lamictal)
36
which of the following sets of lab orders ould be most appropriate when conduction therapeutic drug monitoring for valproic acid?
Drug level, LFTs, platelets.
37
Which gland secretes mineralocorticoid and glucocorticoid hormone?
Adrenal gland
38
97. Which side effect of Lexapro is NOT transient and does NOT subside with continued use?
Sexual dysfunction
39
therapeutic qualities of corticosteroids include?
Anti-inflammatory
40
99. Which side effects occur most commonly with antidepressants?
Dysgeusia and xerostomia
41
A stress steroid cover dose of 10-25mg of hydrocortisone should be used for those with Addison’s Disease who are at high risk of adrenal crisis in which of the following?
Major dental surgery
42
101. What are the most common side effects associated with Remeron use?
Sedation and weight gain
43
Which antidepressant may be associated with an increased risk of bleeding and bruising during and/or after a dental procedure?
Prozac
44
Which of the following are involved in the stimulation of the adrenal gland?
Hypothalamus and pituitary
45
Fludrocortisone is a/an:
Mineralocorticoid
46
Which antidepressant has been associated with bruxism?
Celexa
47
Which of the following adverse effects is associated with the use of corticosteroids?
Suppression of response to infection and insomnia
48
A dose reducing taper should be employed for a patient who receives prednisone for ____ days or more to avoid adrenal insufficiency?
14 days (2 weeks) or longer
49
108. Proper disposal of short acting opioids includes all of the following options except:
Flushing down the toilet.
50
Which medication DOES NOT possess anelgesics and anti-inflammatory properties?
Acetaminophen
51
CP is a 59 y.o. undergoing endodontic treatment. MI one year ago?
Oxycodone
52
111. Patients may experience increased CNS depression from benzodiazepines when suffering from uncontrolled?
Hypothyroidism
53
Which antidepressants pharmacology involves increasing both NE and serotonin levels in the brain?
All the above
54
Which of the following is indicated to treat hyperaldosteronism?
Spironolactone
55
Which MAO-I drug interaction can cause hypertensive crisis?
Tranylcypromine (Parnate) + pseudoephedrine (Sudafed)
56
Mineralocorticoids role in the body is to regulate:
Water and electrolyte balance
57
If a patient presents to the dental clinic with an oral infection that requires antibiotic therapy, but possesses a sulfa allergy, you should avoid sulfa based antibiotics such as sulfamethoxazole-trimethoprim Bactrim DS. If a patient for epilepsy, which of the following anti epileptics should also be avoided in a patient with a sulfa allergy?
Zonsamide Zonegran
58
Liver func2on and platelet test
Valproic acid?
59
Oxycarbamazipine?
SIADH
60
Divalproic acid?
Thrombocytopenia
61
Carbmazapine?
D and Ca supplement
62
Keppra?
Renal func2on test
63
Prozac?
Decrease platelet aggrega2on.
64
Celexa?
Bruxism
65
increase NE and sero
all
66
Hypothyroidism?
Increase in opioid seda2on effects
67
Hyperthyroid increase
epidemic effects
68
Hyperaldosteronism?
Spironolactone
69
Mirtazipine:
highest risk of dry mouth (compared to SSRI and SNRI)
70
Sexual dysfunc2on:
not transient
71
TCA’s (nortryl2line, amtryp2line) casue
increase seda2on from opiods
72
Naloxone can be given
every 2-3 minutes
73
Need to taper cor2costeroid a_er
14 days
74
Pregabalin?
Seizure med can also be used for neuropathic pain or pe:
75
celicoxib
Selec2ve Cox 2 inhibitor
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