ARTHRITIS: 68

Question 1

How is Arthritis classified?

Answer 1

-NONINFLAMMATORY
-Osteoarthritis
- idiopathic (primary
-secondary
-Traumatic
-Coagulopatic

-INFLAMMATORY
-immune mediated
-erosive
-nonerosive
-infective
-crystal induced

Question 2

cell count for osteoarthritis

Answer 2

2-5 x 10^9 total; 88-100 mononuclear cells; 0-12 neutrophils

Question 3

cell count rheumatoid arthritis

Answer 3

8-38 x 10^9 total; 20-80 momonuclear cells; 20-80 neutrophils

Question 4

cell count nonerosive IMPA

Answer 4

4-370 x 10^9 total; 5-85 momonuclear cells; 15-95 neutrophils

Question 5

cell count infective arthritis

Answer 5

40-267 x 10^9 total; 1-10 momonuclear cells; 90-100 neutrophils

Question 6

what are tissues involved in nociception with osteoarthritis?

Answer 6

initially sinovium, later with carticlage damage subchondral bone

Question 7

COX 1 to COX 2 ratio Carprofen

Answer 7

17 (cox 2 selective)

Question 8

COX 1 to COX 2 ratio Firocoxib

Answer 8

342 to 430

Question 9

COX 1 to COX 2 ratio Meloxicam

Answer 9

3

Question 10

COX 1 to COX 2 ratio Robenacoxib

Answer 10

140

Question 11

percentage of dogs cured and relapsed with Type 1 IMPA

Answer 11

56% definitive cure
31% relapse

Question 12

most common drug related to IMPA

Answer 12

Sulfonamides

Question 13

How is called the invasive tissue found in joints with erosive IMPA?

Answer 13

Pannus

Question 14

What are the three most specific criteria for canine Rheumatoid arthritis?

Answer 14

1) destructive radiographic changes typical of RA
2) positive agglutination test for rheumatoid factor
10) histo changes in synovial membrane:
-marked villous hypertrophy
-proliferation superficial synovial cells
-marked inflitration of chronic inflammatory cells

Question 15

common bacteria for septic arthritis in dogs and cats

Answer 15

DOGS: Staph intermedius, aureus; Streptococci
CATS: pasteurella multocida, Bacterioides