Terapia 1 > Artrites e Gotas > Flashcards

Artrites e Gotas Flashcards

(21 cards)

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1
Q

Metotrexato

A

(artrite reumatóide) Fármaco modificador da doença - imunossupressor, inibidor da di-hidrofolato redutase

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2
Q

Hidroxicloroquina

A

(artrite reumatóide) Fármaco modificador da doença

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3
Q

Leflunomida

A

(artrite reumatóide) Fármaco modificador da doença - imunossupressor, inibidor da di-hidro-orotato desidrogenase

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4
Q

Sulfassalazina

A

(artrite reumatóide) Fármaco modificador da doença - anti-inflamatório intestinal

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5
Q

Adalimumab

A

(artrite reumatóide) Fármaco biológico - anticorpo monoclonal anti-TNFα

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6
Q

Infliximab

A

(artrite reumatóide) Fármaco biológico - anticorpo monoclonal anti-TNFα

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7
Q

Abatacept

A

(artrite reumatóide) Fármaco biológico - inibidor de TNFα, IL2 e interferão-γ

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8
Q

Rituximab

A

(artrite reumatóide) Fármaco biológico - Anticorpo monoclonal anti-CD20

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9
Q

Tocilizumab

A

(artrite reumatóide) Fármaco biológico - anticorpo monoclonal anti-IL6

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10
Q

Tofacitinib

A

Imunossupressor inibidor da JAK (Janus cinase)

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11
Q

Ácido hialurónico

A

(Osteoartrite/artrose)

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12
Q

Glucosamina

A

(Osteoartrite/artrose) constituinte da matriz da cartilagem

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13
Q

Condroitina

A

(Osteoartrite/artrose) inibe degradação da cartilagem e estimula a síntese de colagénio

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14
Q

Diacereína

A

(Osteoartrite/artrose) inibe ação das citosinas pró-inflamatórias e da IL-1β

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15
Q

Paracetamol

A

(Osteoartrite/artrose) inibidor da COX3 - impede síntese de PGs a nível SNC

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16
Q

Colquicina

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A

(gota) alcalóide com ação anti-inflamatória

17
Q

Alopurinol

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A

(gota) inibidor da xantina oxidase, diminui os níveis de ácido úrico

18
Q

Febuxostate

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A

(gota) inibidor da xantina oxidase, diminui os níveis de ácido úrico

19
Q

Probenecida

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A

(gota) uricosúrixo - promove excreção renal de ácido úrico

20
Q

Pegloticase

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A

(gota) uricase recombinante - forma recombinante da enzima uricase, responsável por degradar ácido úrico em alantoina

21
Q

Indometacina

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A

(gota) AINE inibidor da COX1

Terapia 1
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