1
Q
Class
A
Muscarinic receptor
antagonist
2
Q
Actions
A
Inhibits secretions Tachycardia Relaxes smooth muscle Antiemetic
3
Q
Mechanism of action
A
Competitive reversible
antagonism at all
muscarinic receptors
4
Q
Clinical use
A
Pupil dilation for eye examination Urinary incontinence IBD Antidote for anticholinesterase poisoning Treatment for cardiac slowing
5
Q
Adverse effects
A
Constipation Reduucing sweating Dry mouth Urinary retention Blurred vision Raised intraocular pressure CNS excitement
6
Q
where does Atropine bind to and what does it do to it
A
the muscarinic acetylcholine receptor and it inhibits it
7
Q
in adequate does what does atropine do?
A
- abolish various types of reflex vagal cardiac slowing or asystole
- prevents or abolishes bradycardia or asystole produced by injection of choline esters, anticholinesterase agents or other parasympathomimetic drugs
- cardiac arrest produced by stimulation of the vagus.
- may also lessen the degree of partial heart block when vagal activity is an etiologic factor.
Block 1 Pharmocology
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