AUB Flashcards

(72 cards)

1
Q

What thickness is diagnostic for endometrial hyperplasia in a PREmenopausal woman?

A

> 15 mm

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2
Q

What thickness is diagnostic for endometrial hyperplasia in a POSTmenopausal woman?

A

> 8mm

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3
Q

What is adenomyosis?

A

Endometrial tissue extending into the myometrium.

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4
Q

What is the most common symptom of endometriosis?

A

Bad cramping during menses. (Dysmenorrhea) that are not helped with pain medication.

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5
Q

Why does endometriosis cause infertility?

A

Scarring that can impede sperm from reaching the egg or for an embryo to implant.

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6
Q

What is the frequency of a normal menstrual cycle (days)?

A

24-38 days (Varneys) or 21-34 days

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7
Q

How many days of menstrual bleeding is considered prolonged?

A

> 8 days

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8
Q

How many days of variation is considered normal for a menstrual cycle to last?

A

7-9 days or less.

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9
Q

What is an average amount of blood loss during menses?

A

30 mL

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10
Q

How many years after onset of menstruation does a cycle become regular?

A

3 years

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11
Q

How many years will a cycle lengthen before menopause?

A

2-4 years

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12
Q

What age range does menopause occur?

A

45-55 years

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13
Q

Is the menstrual cycle length determined by the follicular or luteal phase?

A

Follicular (First half of menses that starts with bleeding and ends with ovulation)

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14
Q

What is the P in PALM-COEIN?

A

Polyp

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15
Q

What is the A in PALM-COEIN?

A

Adenomyosis

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16
Q

What is the L in PALM-COEIN?

A

Leiomyoma

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17
Q

What is the M in PALM-COEIN?

A

Malignancy/Hyperplasia

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18
Q

What is the C in PALM-COEIN?

A

Coagulopathy

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19
Q

What is the O in PALM-COEIN?

A

Ovulatory dysfunction

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20
Q

What is the E in PALM-COEIN?

A

Endometrial

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21
Q

What is the I in PALM-COEIN?

A

Iatrogenic

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22
Q

What is the N in PALM-COEIN?

A

Not otherwise classified

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23
Q

Which AUBs are measurable by imaging or histopathology? PALM or COEIN

A

PALM

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24
Q

Where do uterine polyps grow from?

A

mucous membranes from the internal lining of the uterus or cervix

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25
Are uterine polyps usually benign or malignant?
Benign
26
What are sx of uterine polyps?
Asymptomatic with intermenstrual or post-coital bleeding.
27
What size of uterine polyps should be referred for removal?
> 3 cm
28
Does having a cesarean section increase your risk of adenomyosis?
Yes
29
What medication increases risk for adenomyosis?
Tamoxifen (SERM-selective estrogen receptor modulator) used for breast cancer.
30
What are the symptoms of adenomyosis?
Heavy painful periods and chronic pelvic pain.
31
What would the uterus feel like on a pelvic exam with adenomyosis?
Diffusely enlarged, boggy/spongy, mobile, and tender.
32
What is this picture an example of?
Adenomyosis
33
What is the definitive tx for adenomyosis?
hysterectomy
34
What are 3 top management options for symptomatic adenomyosis?
1. NSAIDS 2. Hormonal IUD (decreases endometrial growth) 3. COC
35
What is a leiomyoma?
Fibroids! Fibromuscular tumor in the uterus
36
Do leiomyomas (fibroids) cause pain?
YES! Abdominal, pelvic, low back, dysmenorrhea.
37
What type of menses does a woman experience who has leiomyomas (fibroids)?
Heavy and long menses.
38
What are the 3 areas that distinguish leiomyoma (fibroids) location?
1. Intramural - within uterus muscle wall 2. Submucosal - endometrial cavity 3. Subserosal - under perimetrium
39
Do leiomyomas (fibroids) reduce postpartum?
Yes
40
What is the primary sx of uterine malignancy?
postmenopausal bleeding or AUB
41
What percentage of those with AUB have a clotting disorder?
13%
42
What is the most common clotting disorder?
Von Willebrand disease
43
What labs do you run for Coagulation concerns?
1. CBC 2. Hemoglobin electrophoresis 3. PT/PTT
44
Does AUB-C cause light or heavy menses?
Heavy menstrual bleeding
45
What is the tx for AUB-C?
1. NSAIDs 2. Hormonal Contraception 3. TXA or DDAVP (Desmopressin)
46
What main sx would you see with Von Willebrand?
Easy bruising/bleeding and heavy menstrual bleeding
47
What about NSAIDs helps with heavy menstrual bleeding?
Calms uterine contractions which reduces the amount of blood that is passed.
48
What do AUB-O dx stem from structural or endocrine abnormalities?
endocrine abnormalities
49
What is a thyroid disorder causing AUB an example of? AUB-?
AUB-O
50
What PALM-COEIN is Von Willebrand?
AUB-C
51
What PALM-COEIN is fibroids?
AUB-L
52
What PALM-COEIN is PCOS?
AUB-O
53
What PALM-COEIN is excessive exercise?
AUB-O
54
What PALM-COEIN is uterine cancer?
AUB-M
55
How does excessive exercise cause AUB-O?
Not enough fat to make hormones (that are made from lipids) AND decreases GnRH drive that suppresses LH/FSH.
56
Why does obesity and other metabolic disorders cause AUB-O?
Increased adipose tissue, that store lipids, are metabolically active and can change the estrogen in your system.
57
What are the 3 subcategories of AUB-O?
1. Anovulatory uterine bleeding 2. Ovulatory uterine bleeding 3. Amenorrhea
58
What is endometritis?
Inflammation of the endometrium
59
What PALM-COEIN is pelvic inflammatory disease?
AUB-E
60
What is the tx for endometritis?
1. Acute: same as PID 2. Chronic: Doxycycline 100 mg BID for 14 days.
61
What is the dx with cervical motion tenderness?
PID
62
What is endometriosis and how is it different than endometritis?
Endometriosis is an overgrowth of endometrial tissue growing outside the uterine cavity. Endometritis is inflammation of the endometrium.
63
What is this picture an example of?
Endometriosis.
64
What is this picture an example of?
Leiomyoma (fibroids)
65
What is this a picture an example of?
Uterine polyps
66
Which age group is most affected by endometriosis? 1. 15-25 2. 25-35 3. 35-45 4. 45-60
25-35, during peak childbearing years.
67
Does endometriosis cause painful periods?
YES! Painful heavy menses and back pain
68
What is the gold standard for dx of endometriosis?
surgical biopsy
69
What is the First-line Tx for endometriosis?
1. OCP + NSAIDs 3. POP+NSAIDs
70
What are natural treatments used for endometriosis?
soy and turmeric
71
What PALM-COEIN is AUB from SSRI use?
AUB-I
72
What PALM-COEIN is AUB from COC?
AUB-I