List the 3 sections the ear is divided into.
Outer, middle and inner ear
Each part has a specific function during the hearing process.
Where is the ear embedded?
The organ is embedded in the petrous portion of the temporal bone
What is the hardest bone in the body?
Petrous portion of the temporal bone
What are the 2 outer ear structures?
Pina and external auditory meatus
List the outer ear functions.
To capture sound and to focus it to the tympanic membrane.
To amplify some frequencies by resonance in the canal.
To protect the ear from external threats (cilia prevents external elements from entering in from the air), the wax provides a mechanical function by covering the inner ear and provides an unfavourable pH to pathogens.
What is the main function of the middle ear?
Amplification by:
What 3 structures articulate with each other to facilitate the transmission of sound into the inner ear?
Malleus, incus and stapes
What is the hearing part of the inner ear?
Cochlea
Describe the relationship between surface area and pressure.
Inversely proportional
What is the function of the inner ear?
To transduce vibration into nervous impulses. While doing so, it also produces a frequency (or pitch) and intensity (or loudness) analysis of the sound.
The cochlea contains 3 compartments. Name them.
Scala vestibuli
Scala media
Scala tympani
What 2 compartments of the cochlea are bone structures containing perilymph (high in sodium)?
Scala vestibuli and scala tympani
What is the Scala media?
Membranous structure containing potassium-rich endolymph. The hearing organ, the Organ of Corti resides within the scala media of the cochlea.
Is the perilymph high in sodium or potassium?
Perilymph HIGH IN SODIUM whereas endolymph is high in potassium.
Where is the hearing organ or Organ of Corti located?
Scala media of cochlea
What is the name of the structure that the organ of Corti lies in?
Basil membrane
Describe how the basilar membrane is arranged.
Arranged tonotopically using the same principle as a xylophone whereby frequency-sensitive cells are arranged from high to low frequency from base to apex respectively.
Explain the arrangement of hair cells in the Organ of Corti.
Contains inner and outer hair cells. Inner hair cells are arranged in single columns whereas outer hair cells are arranged in columns of three.
Where is the tectorial membrane located relative to the hair cells and what is its purpose?
The tectorial membrane is located above the hair cells and will allow the hair deflection, which in turn will depolarise the cell.
Are OHC and IHC in contact with the tectorial membrane?
No, only OHC hair are in constant contact with the tectorial membrane and these assist the contact with the IHC.
What is the function of IHC in the Organ of Corti?
IHC carry 95% of the afferent information of the auditory nerve. Their function is the transduction of the sound into nerve impulses.
What is the function of OHC in the Organ of Corti?
Carry 95% of efferents of the auditory nerve. Their function is modulation of the sensitivity of the response.
Explain the process of transduction.
Deflection of the stereocilia towards the longest cilium will open K+ channels within the inner hair cell, as the tectorial membrane is brought into contact. Ionic interchange of potassium within the endolymph and inner hair cell leads to cell depolarisation. Depolarisation induces the opening of VGCCs which release excitatory NTs (Glutamate) onto the afferent nerve.
What is the relationship between amplitude of sound and deflection of sterocilia causing K+ channel opening?
Higher amplitudes of sound will cause greater deflection of stereocilia and K+ channel opening.