Azoles

Question 1

azoles general info

Answer 1

largest and most versatile group of antifungals
broad spectrum
can be administered PO and have superior safety profile
both systemic and superficial fungal infections

Question 2

two chemical classes

Answer 2

imidazoles

triazoles

Question 3

systemic azoles

Answer 3

spectrum similar to amphotericin B
less toxic
administered PO

Question 4

adverse effects

Answer 4

nausea & vomiting in 10-20% of patients