Name and explain the first stage of the cell cycle.
Interphase/preparation) Cell grows, DNA is replicated, organelle are duplicated
Name and explain the second stage of the cell cycle.
Mitosis) Chromosomes split to each pole of nucleus, nucleus splits into two.
Name and explain the third stage of the cell cycle.
Cytokenesis) Cell wall and membrane split to form two identical daughter cells.
What is a stem cell?
An undifferentiated (unspecialised) cell that can have different genes turned on/off to specialise into a specific type of cell with a specific function
What is a stem cell that can differentiate into all the types of cell in the body called?
Totipotent
What is a stem cell that can differentiate into a few types of cell in the body called?
Multipotent
How many chromosomes does a human have? Where are they located?
46 (23 pairs) in the nucleus of each cell
What are new cells needed for?
Growth, repair (damaged tissue), replacing (worn out cells)
What is a gene?
Small sections of DNA that code for a protein.
What is a chromosome?
Large sections of DNA that contain many genes
What is a zygote?
A sperm cell fused with an egg cell
What is meiosis?
Reduction divison in a cell in which the chromosomes halve from diploid to haploid to form 4 non-identical gametes (sex cells)
Where are stem cells found in plants?
Meristems
What are the sources of embryonic stem cells?
Aborted embryos, spare embryos donated from IVF
What are the problems with using adult stem cells for transferring stem cells?
They could be infected, causing the recipient to also get infected.
They could be rejected by the immune system, which creates a need for immunosuppressant dugs, which can increase succeptibility of infection.
What is therapeutic cloning?
Removal of cells from a patient, and using them to derive a cloned early embryo of the patient. Stem cells are removed from this and used to grow and differentiate into different tissues and organs, which could then be transplanted to the patient. They would be seen as ‘self’ by the immune system and face no risk of immunal rejection.
How can plants be cloned?
By cutting up a leaf and placing it into a growth medium
What are the cons of therapeutic cloning?
Expensive, slow, difficult to control
Embryo dies
Cancer possibility
Consent of donor needed
Collection of egg cells is painful
What are the pros of therapeutic cloning?
Patient specific stem cells-lessens rusk of immunal rejection
Organ donors are not needed
Any type of tissue can be produced
Why is therapeutic clonig used?
To producenan embryo with the same genes as patient to retrieve stem cells and differentiate
Avoid rejection
Discuss the ethical issues surrounding the use of embryonic stem cells in medicine and research.
Some people feel that embryonic stem cells from human embryos shouldn’t be used for experiments since each one is a human life or has the potential to be a human life.
* Some people may argue that there are other sources of stem cells that scientists could use, so using embryos to create stem cells is unjustified.
* Some people think that using embryonic stem cells to cure patients who already exist and who are suffering is more important than the rights of embryos.
* Some people argue that many embryonic stem cells are sourced from unwanted embryos from fertility clinics, which would probably be destroyed anyway.