Bacterial pathogens GU

Question 1

Chlamydia

• Micro
• Types
• A/S
• S/S:
• Complications
• LabDx
• Tx

Answer 1

• M: Gram - cocci; LPS
• Types: A/B/Ba/C -> Trachoma; D-K -> GTI/STI; L1-2 -> LGV
• A/S: FHK Syndrome; Reiter Syndrome
• S/S: Discharge, bleeding, dyspareunia, rectal discharge, conjunctivitis, scrotal swelling/pain
• Complications: Salpingitis, Tuboovarian cysts -> peritonitis
• LAb: NAAT Test
• Tx: Azithromycin or Doxy

Question 2

Neiss. Gono

• Micro
• Compications
• LabDx:
• Patho
• Tx

Answer 2

• M: Diplococci gram - in PMNs
• Comp: INC risk HIV, Opthalmia neonasturum, PID, Epidydimitis, DGI, + death
• LabDx: NAAT; Culture on Thayer Martin
• Path: Interact w/ nonciliated epithelium ancd enter PMNs and use IgA protease to downregulate CD4+ TCs + Kill B Cells;
• Tx: Ceftriaxone + Azithromycin

Question 3

Haem. Duc.

• Micro
• S/S

Answer 3

• M: gram - Pleomorphic; Clumpin “school of fish”

- S/S: Chancroid similar to Syph;

Question 4

Leptospira

• Micro
• EPI
• S/S
• A/S
• LabDx:
• Tx

Answer 4

• M: Small spirochete gram
• Epi: Rodent, dogs, + farm animals;
• S/S: Flu-like s/s; myalgial erythematous maculopapular rash; photophobia
• A/S: Weil Syndrome ->Renal failure
• LabDx: Leptospira antigen
• Tx: Penicillin, macrolide, or Doxy for phrophylaxis

Question 5

Gardnerella Vag

• Micro
• S/S
• LabDx
• Tx

Answer 5

• Pleomorphic gram variable
• S/S: vag itch, burning, nonpainful, gray discharge, smell like dead fish,
• LabDx: Clue Cells; amine whiff test;
• Metronidazole; Clindamycin