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Bacterial Virulence Flashcards

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1
Q

Define Virulence.

A

The capacity of a microbe to cause damage to the host.

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2
Q

What is the function of Adhesins?

A

Attachement of bacteria to the extra cellular matrix of host cells.

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3
Q

How does the superantigen TSST-1 act?

A
  • it causes toxic shock

- triggers mass cytokine release

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4
Q

What bacgterium produces TSST-1?

A

Staph areus

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5
Q

The Staph areus toxin, Panton-Valentine Leukocidin can cause what conditions?

A

Necrotizing pneumonia

Severe skin infections

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6
Q

A clinically relevant Group A Streptococcus (GAS)?

A

Streptococcus pyogenes

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7
Q

Stret pyogenes is __ haemolytic

A

beta

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8
Q

What feature of Strep pyogenes enables it to adhere to Keratinocytes?

A

The hyaluronic acid capsule.

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