vascular: increased total blodo volume, altered stroke volume and CO, HTN
MSK: OA
adipose tissue: increase production of adipokines
liver: non-alcoholic fatty liver disease, NASH
pancreas: insulin resistance, T2DM
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2
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BMI
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Q
male and female obesity numbers
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waist circumference > 40 for men and > 36 in for women considered indicative of central obesity
waist to hip ratio > 1.0 in males and > 0.85 in female suggestive of central obesity
want peripheral fat distribution (pear shape or gluteofemoral obesity) in women - associated with lower relative incidence of obesity related risk factors than apple shape/central fat distribution