Basic Principles

Question 1

Three important drugs that follow zero order kinetics

Answer 1

ethanol
aspirin
phenytoin

Question 2

Name the the 4 most common strong inducers of drug metabolism

Answer 2

carbamazepine
phenobarbital
phenytoin
rifampin

Question 3

List 3 drugs that inhibit metabolism of other drugs

Answer 3

amiodarone
cimetidine
azole antifungals
ritonavir

Question 4

Describe the effects of smoking, liver disease and kidney disease on drug elimination

Answer 4

Smoking - enzyme induction in the liver and lung increasing the metabolism of some drugs.