Automonic nervous system
Sympathetic NS
- Fight/flight
- Epinephrine, norepinephrine, dopamine neuronsmitters
- Alpha,Beta,dopamine receptors
Parasympathetic NS
- Rest/digest
- Acetylcholine neurotransmitter
- Muscarinic receptors
Anticholinergics
Block action of acetylcholine aka parasympathetic system
Acetylcholinesterase inhibitors
Block acetylcholiesterase from breaking down acetylcholine- increasing level and duration of action of acetylcholine
Antidote to anticholinergic poisoning
Amphetamines
- ADHD , narcolepsy treatment
- Enhanced release and reduced uptake of NE and Dopamine
SSRI- selective serotonin reuptake inhibitors
- Escitalopram(newer version of citalopram)
- Citalopram
- Fluoxetine
- Paroxetine
- Sertraline
SNRI- selective serotonin and norepinephrine reuptake inhibitors
- Duloxetine
- Venlaflaxine
ACE (angiotensin-converting enzyme) inhibitors
- Lisinoprol
- Captopril
- Enalapril
Angiotensin 2 receptor blocker
- Losartan
- Valsartan
- Irbesartan
Calcium channel blockers
- Amlodipine
- Nifedipine
- Diltiazem
(Blood pressure control)
Alpha 1 blockers
- Terazosin
- Prazosin
(Hypertension)
Alpha 2 agonists
- Guanfacine
(Hypertension)
Beta blockers
Beta 1 selective
- Metoprolol
- Atenolol
- Nebivolol
Beta non selective
- Propranalol
Beta non-selective/Alpha selective
- Carvedilol
- Labetalol
Diuretics
Loop diuretics
- Furosemide
Thiazide diuretics
- Hydrochlorthiazide
Posatium sparing diuretics
- Spirinolactone
Cardiac glycosides
- Organic steroid structure
- Indicated for heart failure and atrial fibrillation
- Low TI
- Inhibit sodium-potasium pumps which normally exchanges intracellular sodium with extracellulat potasium
- Experience competitive binding with extracellular potasium
- Results in positive inotropic effect(better heart contraction)
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Inflammatory pain mediators
- Bradykinin, norepinephrine, histamine stimulate pain fibres
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland
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