1
Q
antianginal effects
A
Decreases:
- -HR (in exercise)
- -contractility (in exercise)
- -afterload
Does NOT decrease:
- -preload
- -coronary vasospasm
2
Q
Rationale for combining w/ nitrates
A
Reduces:
- -LVEDP
- -LV volume
- -dilates coronary arteries
BBs prevent reflex tachycardia and positive inotropic effect
3
Q
Rationale for combining w/ DHPs
A
- -prevent coronary vasospasm
- -reduce systemic vascular resistance
BBs prevent reflex tachycardia and positive inotropic effect
