MOHDIII - Unit 2 > Beta-Blockers > Flashcards

Beta-Blockers Flashcards

(20 cards)

Study These Flashcards
1
Q

Nebivolol use

A
  • pulmonary HTN
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2
Q

Carvedilol use

A

heart failure

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3
Q

labetalol use

A

HTN

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4
Q

Cardioprotective mechanisms of B-blockers

A
  • reduce SNS, balance myocardial O2 supply/demand ratio
  • increase threshold for ventricular fibrillation in presence of ischemia
  • may increase stability of coronary atherosclerotic plaques
  • may reduce myocardial O2 consumption by suppressing lipolysis, causing myocardium to metabolize for glucose instead of FAs
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5
Q

Mortality & B-blockers

A
  • one of few drugs that have been shown to DECREASE mortality
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6
Q

Special effect seen with carvedilol

A
  • carvedilol improves insulin sensitivity compared w/ metoprolol and atenolol
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7
Q

Very selective B1-blockers

A
  • nebivolol
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8
Q

SENIORS Trial

A
  • nebivolol vs. placebo

- age 70 or older w/ HF: admission for CHF, EF

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9
Q

Urgent treatment of tachycardia drug

A

Esmolol

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10
Q

tachycardia drug

A

propanolol

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11
Q

perioperative SVT drug

A

esmolol

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12
Q

Recurrent AF and AFL drug

A

sotalol

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13
Q

Ventricular rate control in AF

A

propranolol

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14
Q

Dig-induced tachycardia drug

A

propanolol

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15
Q

PVC control drug

A

acebutalol, propranolol

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16
Q

Life threatening VT

17
Q

Labetalol

Study These Flashcards
A
  • ISA plus alpha blockade

- use: malignant HTN, PHEOCHROMOCYTOMA

18
Q

Verapamil

Study These Flashcards
A
  • CCB, liver metabolized
  • more potent AV nodal blockade than diltiazem
  • drug of choice for multifocal atrial tachycardia, ILVT
  • pulmonary friendly
19
Q

Diltiazem

Study These Flashcards
A
  • CCB, renal metabolism
  • IV & PO forms available
  • both verapamil & diltiazem synergistic with beta blockers aka. add a low dose of other class instead of pushing up dose of primary agent*
20
Q

Nadolol

Study These Flashcards
A
  • B blocker
  • LONG half life: 12-24 hrs
  • low lipophilicity
MOHDIII - Unit 2
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