The chemistry of life.
Study of the chemical substances found in living organisms and the chemical interactions of these substance with each other.
Biochemistry
Interdisciplinary Science of Biochem
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The Human Body:
Organic Components
BIOMOLECULES
proteins
carbs
lipids
nucleic acid
NITROGENOUS NON-PROTEIN
coenzyme(vitamin)
amine hormone
Properties of Water
Universal Solvent
High boiling, Low freezing
Cells possesses subcellular structures called
ORGANELLES
carbs
protein
Polynucleotides
lipids
sugar
amino acid
rna dna
fatty acid glycerol
Basic Properties of a Cell
All living cells fall into one of three broad categories—
Archaea, Bacteria and Eukarya.
a group which are single-celled organisms that lack nuclei and other organelles.
prokaryotes
have true nuclei and other organelles such as mitochondria.
Eukaryotic cells
the control center of the cell and contains the genes (chromatin).
Nucleus
site of ribosomal RNA synthesis
Nucleolus
segregates chromatin DNA + protein) from cytoplasm.
Nuclear envelope
Mitochondrion convert the energy in the bonds of ___ and___ to readily available energy in the form of ATP
glucose, oxygen
– internal volume enclosed by plasma membrane.
Cytoplasm
cytosol
– are protein-synthesizing machines
Ribosome
Lysosome
primarily involved in the synthesis of membrane proteins and protein from the cell.
Rough Endoplasmic Reticulum
functions include lipid synthesis and drug metabolism.
Smooth Endoplasmic Reticulum
processes, packages and targets proteins to other organelles or for export.
Golgi Apparatus
separates cell from environment, regulates movement of materials into and out of cell.
Plasma membrane
Methods for separating organelles from cytosol and from each other, WHO DEVELOPED THEM
Albert Claude, Christian de Duve and George Palade
– cells or tissues in solution are gently disrupted by physical shear. It ruptures the plasma membrane but leaves most of the organelles intact.
Cell fractionation