What is the role of the endocrine system
-keeps internal environment of body consistent
- this is called homeostasis
What is a gland
An organ that secretes chemicals known as hormones
Examples of exocrine glands
sweat glands, salivary gland’s, and alimentary glands
What is an exocrine gland
secretes chemicals through a duct that carries them to body surface or body cavities
What is an endocrine gland
-secretes chemicals into extracellular fluid that surrounds cells of gland
-passes into capillaries to be transported by blood
What is a hormone
A chemical secreted from an endocrine gland and transported via blood
What do hormones bind to
a target cell or organ that they are specific to
How are protein receptors specific
they only allow specific molecules to bind to it
How can saturation occur with hormone reception
What is the effect of hormones
Changes the function of a cell by changing its type, amount and/or activity of the protein being produced by the cell
Hormones can:
What is the process of paracrine
Protein/Amine Hormones
Protein/Amine Hormone example
Insulin binds to receptors on the target cells membrane causing an increase in glucose absorption by the cell
Steroid Hormones
-lipid soluble
-travels in the blood on transport proteins
-diffuses through membrane and attaches to receptors on organelles
What can a Hormone receptor complex do
binds to promoter section of a certain gene, stimulating/inhibiting transcription and therefore protein synthesis
What is enzyme amplification
one hormone activating thousands of enzyme molecules
steps of enzyme amplification
hormone clearance
e.g breakdown by enzymes
insulin broken down by enzymes in the liver after it lowers blood sugar
e.g removal by the kidneys
adrenaline
e.g cell absorption and recycling
Thyroid hormones can be stored in cell for later use
What is the Hypothalamus
-a section of the brain that regulates functions of the body e.g body temp + heart rate
-this is carried out through the pituitary gland
- connects endocrine and nervous system
What is the Pituitary gland
a gland located in the brain that’s separated by an anterior and posterior lobe that regulates bodily functions