BIOCHEM 35

Question 1

PGI, PGE, PGD decrease

Answer 1

platelet aggregation, Leukocyte aggregation

IL1, IL2 T-cell proliferation

Question 2

PGI, E, D increases

Answer 2

vasofilation, cAMP

Question 3

PGFa increases

Answer 3

vasoconstriction, bronchoconstriction, SM constraction

Question 4

Primary function of COX-1

Answer 4

platelet aggregation, STOMACH CYTOPROTECTION

Question 5

primary function of COX- 2

Answer 5

Inflammation, hyperalgesia

Question 6

LTB4

Answer 6

increases vascular permiability, T cell proliferation, leukocyte aggregation, INF-y, IL1, IL2

Question 7

LTC4 and LTD4

Answer 7

increase bronchoconstriction, vascular permeability, INF-y