What is a gene
a gene is a small packet of information that controls a characteristic or part of a characteristic. It is a section of a chromsome, which is made by DNA
how many chromosomes do you have in the nucleus of your body cells
46 chromosomes, arranged in 23 pairs
how do body cells divide
body cells divide in a series of stages called the cell cycle
What are the steps of the cell cycle?
stage 1:
the longest stage of the cell cycle. the cells grow bigger, increase their mass and they replicate their DNA to form two copies of each chromosome ready for cell division . They also increase the numbers of subcellular structures
Stage 2:
mitosis - one set of chromosomes is pulled to either end of the dividing cell and the nucleus divides
Stage 3:
this is the stage during which the cytoplasm and the cell membranes also divide to form two identical daughter cells. (The cell membrane grows down the middle and then splits)
why is mitotic cell division important?
it is important in the growth and repair and development of multicellular organisms
what are chromosomes?
chromosomes carry the genes that contain the instructions for making both new cells and all the tissues and organs.
what are stem cells
cells that are unspecialised
how long does mitosis take place in plants?
in plants, mitosis takes place throughout their lives
what is the difference between differentiation in plants and animals?
in animals, differentiation happens at an early stage in development but many types of plant cells have the ability to differentiate throughout life
where are undifferentiated cells formed in plants?
active regions of the stems and roots , known as the meristems
where can we source stem cells for us animals?
from embyros (embryonic stem cells) and bone marrow. there are also some embryonic stem cells in the umbilical cord of newborn babies
what do an egg and sperm cell fuse to form
a zygote
what is a zygote
a fused egg and sperm cell
why might stem cells be useful
treatment with stem cells may be able to help conditions such as paralysis and diabetes.
Furthermore, stem cells from plant meristems can be used to produce plant clones quickly and economically to reduce extinction, for research, etc.
You could also make disease resistant plants!!
what are some of the problems with embryonic stem cells/adult stem cells?
there are ethical concerns - some believe that it is a violation of human rights as there is no consent given, and the religious beliefs of others suggest that we shouldn’t interfere with the process of human reproduction
process in developing these therapies has been slow and expensive, hard to control.
since they grow and divide rapidly, there are also concerns with whether they may cause cancer
Also, the adult stem cells could contain viruses and transfer infections to patients or trigger immune response.
what is therapeutic cloning?
an embryo is produced with the same genes as the patient so the stem cells produced are not rejected and may be used for medical treatment
when using stem cells, they need to grow and divide. Name two things the cells may need
glucose and protein/amino acids
give advantages of using stem cells to make organs/parts of the body instead of using a dead human donor
it will not be rejected
can be done immediately
no need to wait for a donor
evaluate the use of stem cells from a patient’s own bone marrow instead of stem cells from an embryo
embryo advantages:
can create many of them in a lab
painless
can become any type of cell
embryo disadvantages:
ethical concerns
more research is needed
bone marrow cells advantages:
no ethical issues
treats SOME diseases
safe technique
bone marrow cells disadvantages:
can be painful
risk of infection
can only treat few diseases
stem cells from human embryos are used to treat some diseases in humans. Explain why.
stem cells are unspecialised, and can differentiate into any type of cell, and can therefore cure lots of diseases. They are also able to divide/multiply