Bleeding

Question 1

Inhibits platelet aggrgation by interfering with GPIIb/IIIa binding to fibrinogen and other ligands

Answer 1

Abciximab

Question 2

Irreversibly inhibits binding of ADP to platelet receptors,reducing platelet agrregation

Answer 2

Clopidogrel

Question 3

Inhibits phophodiesterase -III and increases cAMP in platelets and blood vessels. Inhibits platelet aggrgation and causes vasodilation

Answer 3

Dipyridamole

Question 4

Binds and potentiates effect of antithrombin III on factor Xa. Less effect on thrombin

Answer 4

Enoxaparin

Question 5

Inhibits vitamin K epoxide reductase

Answer 5

Warfarin

Question 6

Binds to thrombin’s active site and inhibits its enzymatic action

Answer 6

Lepirudin