Blood

Question 1

What are the Functions of Blood?

Answer 1

Transport: Nutrients, Respiratory gases, Wastes, Hormones, Temp reg

Acid-base balance

Protection: WBC and plasma proteins

Question 2

What does Blood contains?

Answer 2

ECF: Plasma
ICF: Fluid inside the blood cells

Question 3

What percentage of Body Mass Blood accounts for?

Answer 3

7%

Question 4

Name Blood Volume Terminology

Answer 4

Normovolemia

Hypovolemia

Hypervolemia

Question 5

Normal value of Hematocrit (Ht) and formula?

Answer 5

45%

Ht = Height of Red Blood Column/Height of whole blood column x 100

Question 6

In a normal Ht value, what is the blood volume in a 70kg malle if we know it’s 7% Body Weight?

Answer 6

Blood volume: 2.25L

Volume occupied by RBC: 2.25L

Volume occupied by Plasma: 2.75L

Question 7

What is the composition of Plasma?

Answer 7

H2O: 90%

Ions: Mainly Na+ and Cl-

Nutrients, Respiratory gasses, Wastes

Proteins: 7%, Albumins, Globulins and Fibrinogen

Question 8

How can we separate Plasma Proteins?

Answer 8

By using Electrophoresis

Question 9

How does Electrophoresis work?

Answer 9

By applying a current through a drop of plasma:

• The rate of migration is influenced by the number, the distribution of charges and by the M.W of each protein

Question 10

When does Plasma becomes Serum?

Answer 10

When fibrinogen is absent.

Question 11

Where are the Plasma Proteins synthesized?

Answer 11

Liver: Albumin, Fibrinogen, Globulin (a1,a2,b)

Lymphoid Tissue: Gamma Globulin

Question 12

What happens to Plasma Proteins in case of Renal Disease?

Answer 12

The Plasma Protein level decreases (Albumin, since small–>goes through liver)

Question 13

What happens to Plasma Proteins in case of bacteria infection?

Answer 13

The immune response induce a spike in gamma globulins.