Bone Marrow

Question 1

Bone Marrow components

Answer 1

1. Hematopoietic

2. Vascular

Question 2

Hematopoietic compartment

Answer 2

hematopoietic cells & stromal cells (supporting cells)
red marrow: erythroid & myeloid cells
yellow marrow: adipocytes

Question 3

Vascular Compartment

Answer 3

nutrient artery, vein, etc

Question 4

Location to Take Marrow Specimens

Answer 4

after adolescence: iliac crest occasionally sternum
< 2 yrs: tibia
older children: spines of lumbar vertebrae

Question 5

MLS role in Bone Marrow Procedure

Answer 5

ensures adequacy of sample

prepare BM slides with aspirate

Question 6

Myeloid to Erythroid Ratio

Answer 6

computed from the total # of myeloid cells to the total # of nucleated RBC stages
2:1-4:1