Botox

Question 1

How many units of Botox usually used for glabellar line?

Answer 1

20 units of Botox
50 units of Dysport

Question 2

What is the name of bacteria that is used to make Botox? Is it gram + or -ve? Anaerobic or aerobic? What shape?

Answer 2

Bacterium Clostridium botulinum

Anaerobic

Gram positive

Sporeforming-rpd shaped bacterium

Question 3

How botox works?

Answer 3

By blocking the neuromuscular junction by preventing the, leading to muscle relaxation release of acetylecholine

Question 4

What are the types of botulinum toxin is used in medicine?

Answer 4

A,B (A is the one used in aesthetic)

Question 5

What are the most common botulinum toxin A Formulations?

Answer 5

Ona (botox , Vitabex)

Abo (dysport)

Inco (Xomin)

Question 6

Which type of botulinum toxin has the most diffusion rate?

Answer 6

Dysport

Question 7

Which botulinum toxin does not contain complex proteins and its called the pure form?

Answer 7

Xeomin

Question 8

Which botulinum toxin is less likely to induce resistance?

Answer 8

Xeomin

Question 9

What botulinum toxin can be used in case ptn has developed resistance towards BOTOX OR DYSPORT?

Answer 9

Xeomin

Myobloc ( more for medical)

Question 10

Which botulinum toxin has the fastest onset?

Answer 10

Dysport 2-3 days

Question 11

Which botulinum toxin has the longest effect?

Answer 11

BOTOX then Xeomin

Question 12

Which botulinum toxin has the highest diffusion rate?

Answer 12

Dysport

Question 13

Which botulinum toxin has the least diffusion rate?

Answer 13

Xeomin ( making it ideal for precise ttt )

Question 14

If patient has milk allergy which botulinum toxin we should avoid to use?

Answer 14

Dysport: because it has a trace of the milk protein

Question 15

What ate the absolute contraindications for botulinum toxin use?

Answer 15

1.pregnancy or lactation

2.Skin: Activr infection or malignancy in the intended treatment area

3.sensitivity to botulinum toxin

4.Uncontrolled systemic disease

5.Neutomascular disorders

Question 16

What are the relative contraindications to use botulinum toxin?

Answer 16

1.Coagulopathies or Anticoagulant use

2.body dysmprphic disorder

3.permenant fillers in the intended area

4. Aminoglycoside antibiotics

5.Magnesium sulfate or Succinylcholine

6.scar healing abnormalities

7.ocular or peri-ocular surgery

Question 17

How to dilute a botulinum toxin vial?

Answer 17

For 100 unit vial add 2.5ml

For 50 add 1.25ml of saline

The result is: 4U/ ml

Question 18

At what temperature we can keep the botulinum toxin? And for how long?

Answer 18

In a refrigerator from 2-8°

For maximum 6 weeks

Question 19

How to mix Dysport? And achive 10 units per 0.05ml?

Answer 19

Dysport contains 300 units.

Add 1.5ml of saline to the 300 units
(300÷1.5=200U/ml÷4= 50U per 0.25ml )

Question 20

How to prepare Xeomin?

Answer 20

It comes in 50, 100 units

For 50 add 1.0ml

For 100 add 2.0ml

Result in concentration of units per 1.0ml

Question 21

Which botulinum toxin has to be discarded after 4 hours of use? By the book

Answer 21

Dysport

Question 22

What are the past botulinum toxin instructions?

Answer 22

Avoid massaging

Avoid lying down

Avoid exercise for 24h

Monitor for allergic reaction, swelling, headaches, swelling

Question 23

What are the possible complications for injecting botulinum toxin in the forehead or glabella?

Answer 23

Potosis (eyelid, eyebrow)

Double vision

Inability to close eyelids

Question 24

Which muscle can cause eyelids ptosis?

Answer 24

By causing paralysis to Levator Palpebrea superioris muscles

Question 25

What is the eye drops to use in case of eyelids ptosis?

Answer 25

Apraclonidine 2-3 times daily

Question 26

What complication can happens by deep neck injection using botulinum toxin?

Answer 26

Drooling/ dysphagia

Question 27

What is the name generic name of Botox, manufacturer, origin, onset, duration, and dilution? Price?

Answer 27

1. Botox® Generic Name: OnabotulinumtoxinA Manufacturer: Allergan (AbbVie) Country of Origin: USA Onset: 3–5 days Duration: 3–4 months Dilution (common):, dilution 100 units + 2.5 mL saline → 4 units per 0.1 mL Price: Around 500–850 AED per 100-unit vial (retail/clinic pricing) 💉 Injection session cost: approx. 1,500–3,500 AED depending on area and clinic Key Notes: Considered the gold standard in Botox products FDA-approved with the most extensive safety data Minimal diffusion; great for precision (e.g., crow’s feet, frown lines)

Question 28

What is the name generic name of dysport, manufacturer, origin, onset, duration, and dilution?price?

Answer 28

Generic Name: AbobotulinumtoxinA Manufacturer: Ipsen Biopharm Country of Origin: UK / France Onset: 2–3 days Duration: 3–4 months Dilution (varies): 300 units + 1.5–2.5 mL saline (Speywood units – not equivalent to Botox units) Price: 💵 Around 5–7 AED per unit (Speywood units) 💵 300-unit vial: ~1,500–1,800 AED 💉 Typical injection session: 750–2,500 AED Key Notes: Faster onset and broader diffusion than Botox Commonly used for large areas like forehead or axillary hyperhidrosis Requires adjustment when converting from Botox due to unit differences

Question 29

What is the generic name of Xeomin, manufacturer, origin, onset, duration, and dilution?

Answer 29

Xeomin® / Bocouture® Generic Name: IncobotulinumtoxinA Manufacturer: Merz Pharmaceuticals Country of Origin: Germany Onset: 4–5 days Duration: 3–4 months Dilution: 100 units + 2.5 mL saline → 4 units per 0.1 mL Price: 💵 Around 25 AED per unit 💵 100-unit vial: approx. 2,200–2,500 AED 💉 Used more in premium aesthetic clinics Key Notes: Contains only the active neurotoxin — no accessory proteins Lower risk of antibody formation over time Stable at room temperature before reconstitution

Question 30

What is the generic name of Nabota, manufacturer, origin, onset, duration, and dilution?

Answer 30

Nabota® (Jeuveau® in U.S.) Generic Name: PrabotulinumtoxinA Manufacturer: Daewoong Pharmaceutical Country of Origin: South Korea Onset: 2–3 days Duration: 3–4 months Dilution: 100 units + 2.5 mL saline → 4 units per 0.1 mL Price: 💵 Around 280–320 AED per 100-unit vial (wholesale price) 💉 Injection sessions: typically 800–1,200 AED Key Notes: Marketed mainly for aesthetic use Popular for fast onset and smooth results Known for good price-to-performance value

Question 31

What is the generic name of Botulax, manufacturer, origin, onset, duration, and dilution?

Answer 31

Generic Name: Botulinum Toxin Type A (letibotulinumtoxinA) Manufacturer: Hugel Inc. Country of Origin: South Korea Onset: 2–3 days Duration: 3–4 months Dilution: 100 units + 2.5 mL saline → 4 units per 0.1 mL Price: 💵 Around 270–350 AED per 100-unit vial 💉 Popular in aesthetic centers offering mid-range pricing Key Notes: Affordable alternative widely used in UAE clinics Korean-made with consistent aesthetic results Often used in budget-conscious aesthetic practices

Question 32

What is the generic name of Letybo, manufacturer, origin, onset, duration, and dilution?

Answer 32

Letybo® Generic Name: LetibotulinumtoxinA Manufacturer: Hugel Inc. Country of Origin: South Korea Onset: 3–4 days Duration: 3–4 months Dilution: 100 units + 2.5 mL saline → 4 units per 0.1 mL Price: 💵 Around 280–360 AED per 100-unit vial 💉 Pricing similar to Botulax, with growing popularity Key Notes: Recent entry in UAE and global aesthetic markets Developed for high purity and lower immunogenicity Similar performance to other Hugel products

Question 33

What is the generic name of Daxxify, manufacturer, origin, onset, duration, and dilution?

Answer 33

Generic Name: DaxibotulinumtoxinA-lanm Manufacturer: Revance Therapeutics Country of Origin: USA Onset: 1–2 days Duration: 6–9 months (longest-lasting Botox) Dilution: Manufacturer-specific; includes peptide excipient Price: 💵 Premium pricing; exact cost varies by clinic 💵 Estimated: ~1,000–1,500 AED per session 💉 Not yet commonly sold as 100U vials in UAE retail Key Notes: Premium option with extended duration Peptide-stabilized formulation; no human or animal byproducts Not yet widely available in UAE clinics — used in select high-end centers

Question 34

How to Dilute Botulinum Toxin Practical Guide? 4 steps

Answer 34

1. Use sterile, preservative‑free 0.9% saline. 2. Withdraw, e.g., 2.5 mL saline into syringe and inject to vial. 3. Gently swirl until fully dissolved—do not shake vigorously. 4. Draw back into insulin syringe (0.01 mL marks). At 100 U/2.5 mL, 0.1 mL = 4 U. At 100 U/4 mL, 0.1 mL = 2.5 U; at 8 mL, 0.1 mL = 1.25 U .