Zygote
Embryo
Fetus
One of the initial three germ layers of the embryo, the source of skin and neural tissue.
Ectoderm
Mesoderm
Endoderm
Neural tube
• Neurons and glia originate from cells located in the____ , a layer of cells lining the inner surface of the neural tube.
ventricular zone
Mitosis
Mitosis/Proliferation
Proliferation
• Once migration is complete and structures have formed (aggregation), axons and dendrites begin to grow to their “mature” size/shape.
Axon Growth/Synaptogenesis
Formation of new synapses
Synaptogenesis
Between 40-75% neurons made, will die after migration - death is normal and necessary !!
• Neurons die due to failure to compete for chemicals provided by targets
Neuronal Death
apoptosis
• By the time a human or other animal is born, much of the wiring of the nervous system is in place.
Neuroplasticity in Adults
• By the time a human or other animal is born, much of the wiring of the nervous system is in place.
Neuroplasticity in Adults
plasticity
critical period
Hebb synapse
imprinting
anencephaly
the caudal portion of the neural tube fails to close normally.
spina bifida
An abnormal genetic condition resulting from a genotype with three copies of chromosome 21, responsible for moderate mental retardation and a characteristic physical appearance.
Down syndrome
A heritable genetic disorder that produces cognitive and physical abnormalities.
fragile-X syndrome