The brain consists of roughly?
-20 billion neurons
Major regions and landmarks of the brain
Cerebrum
Cerebellum
- Adjusts output of other Somatic motor centers in brain and spinal cord
Diencephalon
-Thalamus
•Relay and processing centers fir sensory information
-Hypothalamus
•Centers controlling emotions, autonomic functions, and hormone production
Mesencephalon
Pons
- Subconscious Somatic and visceral motor centers
Medulla Oblongata
Four sources of protection and support
-Plate bones of the skull
•Parietal, frontal, occipital, and temporal bones
-Cranial meninges
•Dura Mater, Arachnoid Mater, and Pia mater
Dura Mater consists of two layers
-Periosteal layer: the outer layer of connective tissue that connects to the periosteum of cranial bones.
-Meningeal layer: a deeper supporting layer,
These two layers are separated by a gap containing fluid and blood vessels
•some gaps enlarged into dural sinuses
Dural venous sinuses
- They are lined by ENDOTHELIUM, and their walls are thick but devoid of muscular tissue. They have no valves.
Dural venous sinuses Function
-To receive blood from the brain through the cerebral veins and the cerebrospinal fluid from The subarachnoid space through the Arachnoid villi
Dural folds
3 large dural folds
Arachnoid Mater consists of?
-Arachnoid membrane
•Connects loosely to Dura Mater
-Arachnoid trabeculae
•Connect to the Pia mater
-Subarachnoid space
•Between the Arachnoid membrane and Pia mater, spanned by trabeculae
Pia mater
Blood brain Barrier
-The Lining of cerebral blood vessels consists of simple squamous endothelial cells that are highly interconnected by tight junctions
•This tight junction barrier restricts what materials can pass from capillary to fluid surrounding cells of the CNS.
Cerebrospinal fluid (CSF)
-Completely surrounds and bathed exposed surfaces of the CNS
-Total volume of CSF at any moment is about 150 ml
-Entire volume replaced about every 8 hours
-Brain has four reservoirs of CSF called ventricles
-CSF is produced and maintained by choroid plexus
•Located in each of the ventricles of the brain
•Consists of combination of Specialized Ependymal Cells and capillaries