Breast

Question 1

ALLIANCE(ACOSOG Z1071)conclusion

Impact of RT on LRC in women with N+ Breast Cancer treated with NAC and ALND.

Answer 1

No evidence that omission of RT in patients converting to node negative after NAC compromised outcome

Question 2

NSABP 04 randomization

Answer 2

Simple mastectomy without axillary dissection vs
Simple mastectomy with axillary dissection vs
Simple mastectomy with comprehensive chest wall and regional nodal irradiation