Bronchiolitis: what is the underlying pathology?
Acute inflammation of the bronchioles, most commonly due to RSV.
What percentage of bronchiolitis cases are caused by RSV?
75–80%.
Bronchiolitis: which age group is most affected?
Infants under 1 year, especially between 1–9 months, with peak incidence at 3–6 months.
Why are newborns partially protected from RSV?
Maternal IgG provides early passive immunity.
When is bronchiolitis incidence highest during the year?
Winter months.
What other organisms can cause bronchiolitis besides RSV?
Mycoplasma and adenoviruses.
Which infants are at higher risk of severe bronchiolitis?
Those with bronchopulmonary dysplasia, congenital heart disease, or cystic fibrosis.
What symptoms typically precede bronchiolitis?
Coryzal symptoms and mild fever.
What are the key respiratory features of bronchiolitis?
Dry cough, increasing breathlessness, wheeze, and fine inspiratory crackles.
Why do many infants with bronchiolitis require hospital admission?
Feeding difficulties associated with increasing dyspnoea.
According to NICE, what features warrant immediate emergency referral in bronchiolitis?
Apnoea, seriously unwell appearance, severe respiratory distress (grunting or marked recession or RR >70), central cyanosis, or oxygen saturations <92% in air.
According to NICE, when should clinicians consider hospital referral in bronchiolitis?
RR >60, difficulty feeding or intake 50–75% of normal, or signs of clinical dehydration.
What investigation can confirm RSV in bronchiolitis?
Immunofluorescence of nasopharyngeal secretions.
What is the main approach to bronchiolitis management?
Supportive care.
When is humidified oxygen recommended in bronchiolitis?
When oxygen saturations are persistently <92% in air.
What feeding support may be required in bronchiolitis?
Nasogastric feeding if oral intake is inadequate.
What supportive technique may be used for excessive upper-airway secretions in bronchiolitis?
Suctioning.