Campylobacter

Question 1

General characteristics (3)

Answer 1

Small, Spiral, Gram Negative Bacilli
MOTILE
OXIDASE POSITIVE

Question 2

Pathogenesis (6)

Answer 2

COMMONEST cause of INFECTIVE DIARRHEA in DEVELOPED countries
ANIMALS are main source: POULTRY and RAW MEAT
SMALL INFECTIVE DOSE
DO NOT MULTIPLY in FOOD (SALMONELLOSIS)
Involvement of BOTH SMALL and LARGE INTESTINE
INVASIVE disease

Question 3

Clinical Manifestations (6)

Answer 3

Diarrhea/bloody

GTHR (GI hemorrhage, Toxic megacolon, HUS, Reactive arthritis)

Question 4

Lab Diagnosis (3)

Answer 4

Selective media: Charcoal-based media containing antibiotics
Microaerophilic environment for growth
Temp 42-43 degrees

Question 5

C.jejuni (2)

Answer 5

Hydrolysis Hippurate

90-95% of infections