Cannabinoid

Question 1

Cannabinoid
- Uses

Answer 1

• Prevention of chemotherapy induced nausea and vomiting
• Decreasing spasticity of MS or spinal cord injury
• Preventing seizures in Lennox-Gastaut and Dravet syndrome
• Decreasing pain in chronic neuropathic pain

Question 2

Best Cannabinoid for pain

Answer 2

Nabiximols
- Higher doses may not improve analgesia
- May cause more adverse effects

Question 3

Cannabis and Opioids

Answer 3

Using both Cannabis and Opioids does not seem to decrease opioid use or help more with pain
- May be more nausea and vomiting

Question 4

Approach to Cannabinoid initiation

Answer 4

1. Define goals of treatments
2. Assess for risk of misuse
3. Nabilone or Nabiximol is prefferred (Try to avoid inhaled products)
4. Start low and go slow
5. Reasonable trial may be 12 weeks

Question 5

Cannabinoid
- Inhaled routes

Answer 5

Difficult to dose
Respiratory risk
Variability of composiition

Question 6

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