capsules

Question 1

what are capsules

Answer 1

solid dosage forms in which medicinal agents and/or inert substances are enclosed within a small shell of gelatin

Question 2

capsule shell types

Answer 2

hard gelatin or soft gelatin

Question 3

drug in capsules

Answer 3

powder, granulation, liquid, semi solid mass

Question 4

advantages of capsules

Answer 4

easy to carry, swallow, identify, mask taste, flexible dose (and for combos), cheap, LESS INCOMPATIBILITIES, good for clinical studies

Question 5

Empty Hard Gelatin Capsule Properties

Answer 5

• contain 10- 15% of moisture
  – Stable in air when dry
  – Prone to microbial decomposition when it becomes moist
  – Almost insoluble in cold water
  – Soluble in hot water and in warm gastro-intestinal fluids
  – Digested and absorbed wel

Question 6

composition of hard gelatin capsules

Answer 6

gelatin (pharmagel A and B), sucrose (for shell hardness), sulfur dioxide (for transparency), water