Co-morbidities that inc risk of atherosclerosis
DM
HTN
CKD
Inflammatory conditions ie RA
Psychosis (anti psychotic use)
Primary Prevention of CVD
Based on QRISK 3
10 year risk of MI / stroke
>10% = statin (atorvastatin 20mg)
Statins also offered to all with CKD or T1DM (if had for over 10 yrs or who are over 40)
Secondary Prevention
4As
Antiplatelet
Atorvastatin 80mg
Atenolol (beta blocker)
ACEi
Clop in stroke and vascualr disease
Clinical signs of Familial Hypercholesterolaemia
Simon Broome Criteria
Stable vs Unstable Angina
Stable - bought on by exercise and relieved by rest or GTN
Basic Management of stable Angina
RAMPS
Refer
Advise Dx and safetynet
Medical management
Procedural / surgical Mx
Secondary prevention
Medical Mx of Stable Angina
GTN = vasodilation = improved blood flow to myocardium
Longer term symptom relief - one or both of
Beta blocker or CCB (avoid in Hf)
Specialist:
ISM
Ivabradine
Nicorandil
Ranolazing
Surgical Mx Angina
used with more severe disease and when medical Mx fails
PCI - radial / fem access - inject contrast see stenosis - then can widen artery with balloon (angioplasty) and stent
CABG - midline sternotomy. Graft vessel attached to coronary artert bypassing stenosis
PCI has quicker recovery, lower rate of strokes but has a higher rate of needing rpt vascularisation
Cardiac Syndrome X
Angina-like chest pain without the presence of coronary artery disease when investigated with angiograms
Women 45-55
Dx of exclusion.
Coronary Anatomy
RCA - RA, RV, inferior LV and posterior septum
Left circumflex - LA and posterior LV
LAD - Ant aspect of LV and ant septum
ECG changes linked to anatomy
LCA - 1, aVL, V3-6
LAD - V1-4
Circumflex - 1, aVL, V5-6
RCA - 2,3 and aVF
Things that can rise Trop
Chronic kidney disease
Sepsis
Myocarditis
Aortic dissection
Pulmonary embolism
Initial Mx
CPAIN
Call Ambulance
Perform ECG
Aspirin 300mg
IV morphine if needed
Nitrate (GTN)
STEMI Mx
PCI - if within 2 hours of presentation
Thrombolysis if not
May need another antiplatelet pre PCI
NSETMI Mx
BATMAN
Base the decision of PCI vs thrombolysis on GRACE score
Aspiring 300mg
Ticagrelor 180mg (clopi if high risk)
Morphine
Antithrombin - fonda
Nitrate
Who gets an angio in NSTEMi
GRACE of over 3% - early angiography wiith PCI (within 72hrs)
Types of MI
ACDC
ACS, cant cope, Dead, and Caused
T1 - Traditional MI
T2 - Secondary to inc demand or reduced supply of o2
T3 - Sudden cardiac death from ischaemia
T4 - MI associated with cardiac procedures
How does Pulm oedema occur
Impaired LVF causes backlog of blood. Therefore inc volume and pressure in LA, pulm veins and lungs. Fluid leaks out. around lungs
Causes of Heart Failure
IHD
Valvular Heart disease
HTN
Arrythmias
Cardiomyopathy
Clinical signs of Heart Failure
Murmurs on auscultation indicating valvular heart disease
3rd heart sound on auscultation
Bilateral basal crackles (sounding “wet”) on auscultation of the lungs, indicating pulmonary oedema
Raised jugular venous pressure (JVP), caused by a backlog on the right side of the heart, leading to an engorged internal jugular vein in the neck
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Peripheral oedema of the ankles, legs and sacrum
Why do they get PND
Fluid settles across the large area of the lungs as lie flat. As stand fluid sinks to lung bases - easing symptoms
During sleep, the resp centre is less responsive, so the RR and effort do not increase in response to reduced oxygen saturation = more significant pulmonary congestion and hypoxia before they wake up feeling very unwell.
Less adrenalin circulating during sleep. Less adrenalin means the myocardium is more relaxed, reducing cardiac output.
NYHA classes
1 - no limitation on activity
2 - symptomatic with ordinary activities
3 - symptomatic with any activity
4 - symptoms at rest
Referral Criteria
Urgent if BNP above 2000 (2 weeks)
400-2000 then 6 weeks
Medical MX
ABAS
ACEi (avoid valvular heart disease unless specialist)
Beta bocker
Aldosterone antagonist
SGLT2i