Spectrum size and use (first generation)
Narrow, gram +, prophylactic (surgery)
3rd and 4th Generation spectrum and use
Broad Spectrum, Cross blood/brain barrier, Tx Bact. Meningitis, a lot of gram -, not many gram +
Second Generation spectrum and use
Intermediate spectrum, some gram -, not many +
Cephalosporin’s effect on bacteria
inhibits cell wall synthesis