Action
Binds to bacterial cell membranes, inhibits cell wall synthesis. Bactericidal, used to treat infections
Dosage
250mg to 2 g q6-12h
Infuse over 30 minutes
Side effects
Thrush Diarrhea Abd cramping super infection Sensitivity to antibiotics
Contra indications
Hx of hypersensitivity or anaphylactic reaction to PCN
Absorption
Absorbed circulatory system
Metabolized in liver
Excreted in urine
Nursing interventions
Question for Hx of allergies assess oral cavity Monitor BM I &O Renal function test for nephrotoxicity Be alert for super infection (fever, vomiting, diahrrea, oral changes) Monitor IV site
Classification
1st generation cephalosporin