Ceftriaxone

Question 1

What type of drug is ceftriaxone?

Answer 1

3rd gen cephalosporin antibiotic

Question 2

What are the actions of ceftriaxone?

Answer 2

1. Broad spectrum antibiotic- especially effective against gram negative (-) bacteria eg meningococcus
2. Effective at crossing the blood brain barrier

Question 3

What is the indication for ceftriaxone?

Answer 3

Suspected meningococcal disease in acutely I’ll patients

Question 4

What are the 3 adverse effects of ceftriaxone?

Answer 4

1. Hypersensitivity reactions
2. Diarrhoea
3. Skin rash

Question 5

Contraindications for ceftriaxone?

Answer 5

KSAR to cephalosporins

Question 6

What is the the precaution for ceftriaxone?

Answer 6

20% if patients with penicillin allergy may be sensitive to ceftriaxone

Question 7

What is the ceftriaxone dose for paediatrics and adults?

Answer 7

50mcg/kg to a total of 2g (IV preferred). Make up to 10ml with normal saline and five slowly over 2-4 minutes