Mitosis is defined as…
Nuclear division
Cytokinesis is defined as…
Cytoplasmic division
Kinetochore
Collection of proteins
During prophase, the parts broken down are…
- Nuclear envelope
- Nuclear pore complexes
- Nuclear lamina
During prophase, these are formed by the addition of a phosphate group…
Nuclear membrane vesicles
Give the order of M-phase:
(1) Prophase
(2) Prometaphase
(3) Metaphase
(4) Anaphase
(5) Telophase
Prophase
- Disassemble interphase MT array, form mitotic spindle
- Centrosomes move to opposite poles
- Chromatin condenses
- Nuclear envelope dissociates
Prometaphase
-Kinetochore MTs move pairs of sister chromatids back & forth until they reach metaphase plate
Metaphase
- All pairs of sister chromatids are lined up on metaphase plate
- Connection between chromatids broken
Anaphase
- Anaphase A: kinetochore MTs separate sister chromatids
- Anaphase B: polar MTs “push” & astral MT “pull” poles
Telophase
Undo what was done during prophase
Cytokinesis
Cytoplasmic division using contractile ring of actin & myosin
The Cell Theory
- The cell is the fundamental unit of life
- All living organisms are made of one or more cells
- All cells come from pre-existing cells
_________ cells can be distinguished microscopically.
Mitotic
___________ cells must be distinguished biochemically.
G1-S-G2
___________ cells incorporate radioactive thymidine.
S-phase
Phosphotases
a group of enzymes that remove phosphate groups from molecules
