cell mediated response

Question 1

what are lymphocytes?

Answer 1

white blood cells involved in the specific immune response

Question 2

where are lymphocytes made?

Answer 2

bone marrow

Question 3

what cells are involved in the cell mediated response?

Answer 3

T cells and body cells

Question 4

why is the cell mediated response specific?

Answer 4

because T cells respond to antigens on the surface of cells

Question 5

what are APCs?

Answer 5

antigen presenting cells- any cell that presents a non self antigen on their surface

Question 6

give 4 examples of APCs

Answer 6

infected body cells, macrophages, cells of a transplanted organ, cancer cells

Question 7

why are T cell responses cell mediated?

Answer 7

because T cells only respond to antigen which are presented on APCs and not antigens detached from cells

Question 8

describe the cell mediated response

Answer 8

1. once a pathogen has been engulfed + destroyed by a phagocyte, the antigens are positioned on the cell surface so the P is now an APC
2. tH cells have receptors on their surface which can attach to the antigens
3. this activates the tH cells to divide by mitosis to make clones
4. cloned tH cells differentiate into different cells such as memory cells or cytotoxic T cells