Parts that make up the cell membrane
Two parts of phospholipids and their functions
Phosphate head: Hydrophilic, polar, form hydrogen bonds with water
Fatty acid tail: Hydrophobic, nonpolar, no hydrogen bonds
amphipathic molecule
a molecule with both hydrophilic and hydrophobic regions
Draw a lipid with labeled regions
Three shapes of lipids
Micelle: bulky head and one fatty tails
Bilayer: small head two fatty tails
Liposomes: Spherical form of lipids
What conditions affect the lipid bilayer?
How does Van der Waals forces effect lipid mobility?
The more van der Waals forces the less mobile the lipid becomes
How does saturation effect lipids mobility
Parts of cholesterol
How does Cholesterol affect membrane fluidity?
At normal temperature cholesterol decreases fluidity: rings weigh down lipid
At low temperatures, it increases fluidity.
Cholesterol maintains the cell fluidity no drastic shift from solid to liquid
How do proteins serve the cell?
Two categories for membrane proteins
Integral membrane proteins: are permanently associated with the cell and cannot be separated from the cell without destroying it.
Peripheral membrane proteins: are temporarily associated with the lipid bilayer through weak covalent bonds
Role of integral membrane proteins:
Transmembrane Proteins span the entire lipid bilayer.
- interacts with signaling molecules
- Interacts with the proteins in the cytoplasm
(Draw out the regions )
Experimental proof that proteins move through the cell membrane
Experiment: Fluorescence recovery after bleach is a process where a small area of the cell membrane is bleached while the proteins are dyed. If the bleached part becomes dyed then the proteins traveled there. That is what happened.