What are paracrine signals?
They act over short distances
What are endocrine signals?
Act over long distances through blood and lymph
What are autocrine signals?
Act on the same cell that secretes them
How do ion channels work?
The ligand changes the shape of the channel to allow the ions to move through.
How do G protein gated channels work?
The ligand binding domain associates with a G protein
How do protein-kinase gated channels work?
RTk (tyrosine kinase) associates with the receptor and has a Tyr that can be phosphorylated