Cell Trafficking

Question 1

Topologically equivalent regions

Answer 1

• nucleus and cytoplasm

- perinuclear cistern=ER cisterna=Golgi cisterna =lysosomes= transport vesicles=endosomes=extranuclear space

Question 2

Three major categories of transport

Answer 2

• gated
• transmembrane
• vesicular

Question 3

Gated transport

Answer 3

-large openings act as selective gates for movement of proteins from one compartment to another between topologically equivalent spaces

Question 4

Transmembrane transport

Answer 4

• between topologically different source and target space

- membrane bound translocators transport proteins across membrane from cytosol to wherever dictated by targeting signal

Question 5

Vesicular transport

Answer 5

• material moved between topologically equivalent compartments when both compartments are membrane bound
• movements along cytoskeletal tracts